The Broad Institute is organized around scientific programs and platforms, an integrated and transparent infrastructure that allows biology- and technology-focused scientists to jointly build, apply, and share with scientists worldwide the cutting-edge tools, data, and knowledge needed to revolutionize medical knowledge and practice.

Scientists at the Broad Institute work together to tackle large-scale biomedical challenges, which span the full gamut of biology and medicine. Areas of active research include, but are not limited to:

• Deciphering all the information encoded in the human genome
• Understanding human genetic variation and its role in disease
• Compiling a complete molecular description of human cancers
• Identifying a range of small chemicals that can probe normal biology and disease
• Defining the genetics and biology of infectious disease, especially malaria, tuberculosis,
  and HIV
• Unraveling the molecular basis of major metabolic diseases, including type 2 diabetes, obesity, and cardiovascular disease
• Dissecting the biology of devastating psychiatric diseases, such as autism, manic depression, and schizophrenia disorders